In Europe, a rare disease is defined as a pathological condition affecting less than 1/2000 people and most rare diseases are due to genetical disorders.
Their low frequency generates a lack of visibility, both in medical environments and in social media, which is ultimately responsible for the lack of support and resources.
As data on frequencies, epidemiology and aetiology of rare diseases are largely incomplete, we believe that understanding their history is a crucial step to take in order to increase knowledge and awareness about both the present and the past of rare diseases.